Association between default mode network functional connectivity and plasma p-Tau217 levels in patients with mild cognitive impairment
Shang Zhang, Haoyu Li, Junyao Wang et al. preprint
Background: Mild cognitive impairment (MCI) is a critical stage in the Alzheimer's disease continuum, yet accessible biomarkers reflecting both peripheral pathology and central network dysfunction are insufficient. This study investigated whether default mode network (DMN) functional connectivity correlates with plasma phosphorylated tau 217 (p-Tau217) in MCI patients.Methods: Thirty‑two MCI...