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Stephanie M Groman

1 paper in the library · publishing 2012

Papers

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Asenapine effects on cognitive and monoamine dysfunction elicited by subchronic phencyclidine administration.

Neuropharmacology March 2012 John D Elsworth, Stephanie M Groman, J David Jentsch et al.

Repeated, intermittent administration of the psychotropic NMDA antagonist phencyclidine (PCP) to laboratory animals causes impairment in cognitive and executive functions, modeling important sequelae of schizophrenia; these effects are thought to be due to a dysregulation of neurotransmission within the prefrontal cortex. Atypical antipsychotic drugs have been reported to have measurable, if...