Brinell Arcanjo Moura

Behavioral alterations and pro-oxidant effect of a single ketamine administration to mice.

Brain Research Bulletin August 30, 2010 Francisca Charliane Carlos Da Silva, Maria Do Carmo de Oliveira Cito, Maria Izabel Gomes Da Silva et al.

A growing body of evidence has pointed to the ionotropic glutamate N-methyl-d-aspartate receptor (NMDA) as an important player in the etiology of psychopathologies, including anxiety and major depression. Clinical findings suggest that ketamine may be used for the treatment of major depression. There is evidence that reactive oxygen species also play an important role in the pathogenesis of...