Administration of MDMA to ethanol-deprived rats increases ethanol operant self-administration and dopamine release during reinstatement.
The International Journal of Neuropsychopharmacology August 2009 Guillermo Moreno-Sanz, Esther O'Shea, Laura Orío et al.
Recreational use of (±)-3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is often associated with other drugs, among which ethanol (EtOH) is one of the most common. However, little is known about how neurochemical sensitization produced by MDMA can modulate EtOH abuse. In this study we used EtOH operant self-administration tasks to investigate the effect of several low doses (0.33, 1.0 and 3.0...