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Jaap M Koolhaas

1 paper in the library · publishing 2009

Papers

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MDMA-induced serotonergic neurotoxicity enhances aggressiveness in low- but not high-aggressive rats.

European Journal of Pharmacology September 15, 2009 Alinde E Wallinga, Anna M Ten Voorde, Sietse F De Boer et al.

Ecstasy or 3,4-methylenedioxymethamphetamine (MDMA) is a frequently (ab)used recreational drug for its acute euphoric effects but on the long-term may cause neurotoxic damage to serotonin (5-hydroxytryptamine; 5-HT) nerve endings in the brain. Since decreased brain 5-HT function has been strongly associated with several impulse control disorders like hostility and violent aggression, ecstasy...