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J H Kordower

1 paper in the library · publishing 2012

Papers

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Prenatal exposure to MDMA alters noradrenergic neurodevelopment in the rat.

Neurotoxicology and Teratology 2012 Valerie B Thompson, James B. Koprich, E Y Chen et al.

3,4-methylenedioxymethamphetamine (MDMA; ecstasy) binds with high affinity to the norepinephrine transporter (NET), making the noradrenergic system a potential target during fetal exposure. Recent data indicate that adult rats that had been prenatally exposed to MDMA display persistent deficits in working memory and attention; behaviors consistent with abnormal noradrenergic signaling in the...