Duncan Ryan

Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia.

Neuroscience Letters November 20, 2006 Duncan Ryan, Alison J Drysdale, Roger G Pertwee et al.

We have shown previously that the plant cannabinoid cannabidiol (CBD) elevates intracellular calcium levels in both cultured hippocampal neurones and glia. Here, we investigated whether the main psychotropic constituent of cannabis, Delta(9)-tetrahydrocannabinol (THC) alone or in combination with other cannabis constituents can cause similar responses, and whether THC affects the responses...