Ayahuasca treatment reduces 50-kHz ultrasonic vocalizations and modifies mesocorticolimbic monoamine neurochemistry in rats.
Pharmacology, Biochemistry, and Behavior September 30, 2026 Camila Pasquini De Souza, Vinicius Theiss De Rosso, Daiane Momo Daneluz et al.
Rats emit 50-kHz ultrasonic vocalizations (USVs), a widely used measure of drug-induced motivational and affective effects and dopaminergic activity. Although psychedelic drugs are promising for addiction treatment, the effects of ayahuasca (AYA) on 50-kHz ultrasonic vocalizations (USVs) remain unclear. We investigated whether acute AYA treatment attenuates lisdexamfetamine (LDX)-induced USVs,...
DOI: 10.1016/j.pbb.2026.174274 (opens in new tab)
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Addiction
Serotonin
Amphetamine
Dopamine
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