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Bezhan Chankvetadze

2 papers in the library · 18 citations · publishing 2024

Papers

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Optimization of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its phase-1 metabolites in human biological fluids.

Journal of Pharmaceutical and Biomedical Analysis June 15, 2024 Giorgia Sprega, Giorgi Kobidze, Alfredo Fabrizio Lo Faro et al. 4 citations

Recently we published in this journal an enantioselective high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantitative determination of 3,4-methylenedioxymethamphetamine (MDMA) and its major phase-1 metabolites, 4-hydroxy-3-methoxyamphetamine (HMA), 4-hydroxy-3-methoxymethamphetamine (HMMA) and 3,4-methylenedioxyamphetamine (MDA) in human plasma, sweat,...

DOI: 10.1016/j.jpba.2024.116076 (opens in new tab) Full text (opens in new tab) Chiral hplc Enantioselective metabolism Enantioseparation Hydrolysis of glucuronides +6

Development of enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its phase-1 metabolites in human biological fluids.

Journal of Pharmaceutical and Biomedical Analysis January 20, 2024 Alfredo Fabrizio Lo Faro, Giorgia Sprega, Diletta Beradinelli et al. 14 citations

In the present study enantioselective high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods were developed for the quantitative determination of 3,4-methylenedioxy-methamphetamine (MDMA) and its major phase-1 metabolites 4-hydroxy-3-methoxyamphetamine (HMA), 4-hydroxy-3-methoxymethamphetamine (HMMA) and 3,4-methylenedioxyamphetamine (MDA) in human plasma, sweat,...

DOI: 10.1016/j.jpba.2023.115768 (opens in new tab) Full text (opens in new tab) Chiral hplc Enantioselective metabolism