Δ9-Tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption.
European Neuropsychopharmacology June 2015 Cristina A J Stern, Lucas Gazarini, Ana C Vanvossen et al.
Δ(9)-tetrahydrocannabinol (THC) and cannabidiol (CBD) are the major constituents of the Cannabis sativa plant, which is frequently consumed by subjects exposed to life-threatening situations to relief their symptomatology. It is still unknown, however, whether THC could also affect the maintenance of an aversive memory formed at that time when taken separately and/or in conjunction with CBD....
DOI: 10.1016/j.euroneuro.2015.02.001 (opens in new tab)
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Cannabidiol
Cb1 receptor
Fear memory
Medial prefrontal cortex
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