Conor J Houghton

Behavioural and computational methods reveal differential effects for how delayed and rapid onset antidepressants effect decision making in rats.

European Neuropsychopharmacology December 2017 Claire A Hales, Conor J Houghton, Emma Robinson

Major depressive disorder (MDD) is one of the most prevalent psychiatric disorders. Until the recent discovery of the rapid onset antidepressant action of ketamine, pharmacological treatments for MDD were limited to conventional antidepressant drugs with delayed clinical efficacy. Using a judgement bias task, this study has investigated whether the temporal differences observed in patients...