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Jake Knowles

1 paper in the library · 11 citations · publishing 2024

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Patient-reported outcomes on sleep quality and circadian rhythm during treatment with intravenous ketamine for treatment-resistant depression.

Therapeutic Advances in Psychopharmacology 2024 Raymond Yan, Tyler Marshall, Atul Khullar et al. 11 citations

Intravenous (IV) ketamine is a rapid acting antidepressant used primarily for treatment-resistant depression (TRD). It has been suggested that IV ketamine's rapid antidepressant effects may be partially mediated via improved sleep and changes to the circadian rhythm. This study explores IV ketamine's association with changes in patient-reported sleep quality and circadian rhythm in an adult...