Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents.
European Journal of Pharmacology August 15, 2014 Jenny L Wiley, D Matthew Walentiny, M Jerry Wright et al.
The mechanism through which marijuana produces its psychoactive effects is Δ(9)-tetrahydrocannabinol (THC)-induced activation of cannabinoid CB1 receptors. These receptors are normally activated by endogenous lipids, including anandamide and 2-arachidonoyl glycerol (2-AG). A logical "first step" in determination of the role of these endocannabinoids in THC׳s psychoactive effects is to...
DOI: 10.1016/j.ejphar.2014.05.013 (opens in new tab)
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2-arachidonoylglycerol
Anandamide
Jzl184
Pf3845
+2