Pier Andrea Borea

2 papers in the library · publishing 2016

Papers

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Effect of the novel synthetic cannabinoids AKB48 and 5F-AKB48 on "tetrad", sensorimotor, neurological and neurochemical responses in mice. In vitro and in vivo pharmacological studies.

Psychopharmacology October 2016 Isabella Canazza, Andrea Ossato, Claudio Trapella et al.

AKB48 and its fluorinate derivate 5F-AKB48 are two novel synthetic cannabinoids belonging to a structural class with an indazole core structure. They are marketed as incense, herbal preparations or chemical supply for their psychoactive Cannabis-like effects. The present study was aimed at investigating the in vitro and in vivo pharmacological activity of AKB48 and 5F-AKB48 in male CD-1 mice...

DOI: 10.1007/s00213-016-4402-y Full text 5f-akb48 Behavior Jwh-018 Microdialysis +3

Effect of JWH-250, JWH-073 and their interaction on "tetrad", sensorimotor, neurological and neurochemical responses in mice.

Progress in Neuro-Psychopharmacology and Biological Psychiatry June 3, 2016 Andrea Ossato, Isabella Canazza, Claudio Trapella et al.

JWH-250 and JWH-073 are two synthetic cannabinoid agonists with nanomolar affinity at CB1 and CB2 receptors. They are illegally marketed within "herbal blend" for theirs psychoactive effects greater than those produced by Cannabis. Recently, we analyzed an "herbal" preparation containing a mixture of both JWH-250 and JWH-073. The present study was aimed at investigating the in vitro and in vivo...

DOI: 10.1016/j.pnpbp.2016.01.007 Full text Jwh-018 Jwh-073 Jwh-250 Microdialysis +1