Qammarah Martin

2 papers in the library · publishing 2015-2022

Papers

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Prenatal Δ9-Tetrahydrocannabinol Exposure in Males Leads to Motivational Disturbances Related to Striatal Epigenetic Dysregulation.

Biological Psychiatry July 15, 2022 Randall J Ellis, Anissa Bara, Claudia A Vargas et al.

Cannabis remains one of the most widely abused drugs during pregnancy. In utero exposure to its principal psychoactive component, Δ9-tetrahydrocannabinol (THC), can result in long-term neuropsychiatric risk for the progeny. This study investigated epigenetic signatures underlying these enduring consequences. Rat dams were exposed daily to THC (0.15 mg/kg) during pregnancy, and adult male...

DOI: 10.1016/j.biopsych.2021.09.017 Full text Cannabis Depression Chromatin Epigenetics +2

Genome-Wide DNA Methylation Profiling Reveals Epigenetic Changes in the Rat Nucleus Accumbens Associated With Cross-Generational Effects of Adolescent THC Exposure.

Neuropsychopharmacology December 2015 Corey T Watson, Henrietta Szutorisz, Paras Garg et al.

Drug exposure during critical periods of development is known to have lasting effects, increasing one's risk for developing mental health disorders. Emerging evidence has also indicated the possibility for drug exposure to even impact subsequent generations. Our previous work demonstrated that adolescent exposure to Δ(9)-tetrahydrocannabinol (THC), the main psychoactive component of marijuana...

DOI: 10.1038/npp.2015.155 Full text