Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats.
Pharmacological Research September 2016 Erica Zamberletti, Marina Gabaglio, Massimo Grilli et al.
Cannabis use has been frequently associated with sex-dependent effects on brain and behavior. We previously demonstrated that adult female rats exposed to delta-9-tetrahydrocannabinol (THC) during adolescence develop long-term alterations in cognitive performances and emotional reactivity, whereas preliminary evidence suggests the presence of a different phenotype in male rats. To thoroughly...
DOI: 10.1016/j.phrs.2016.07.008 (opens in new tab)
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Adolescence
Astrocytes
Behavior
Delta-9-tetrahydrocannabinol
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