Potential involvement of serotonergic signaling in ketamine's antidepressant actions: A critical review.
Progress in Neuro-Psychopharmacology and Biological Psychiatry November 3, 2016 Kristian Gaarn Du Jardin, Heidi Kaastrup Müller, Betina Elfving et al.
A single i.v. infusion of ketamine, classified as an N-methyl-d-aspartate (NMDA) receptor antagonist, may alleviate depressive symptoms within hours of administration in treatment resistant depressed patients, and the antidepressant effect may last for several weeks. These unique therapeutic properties have prompted researchers to explore the mechanisms mediating the antidepressant effects of...
DOI: 10.1016/j.pnpbp.2016.05.007 (opens in new tab)
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Ketamine
Serotonin
Antidepressant
Glutamate
+1