Interactive effects of ghrelin and ketamine on forced swim performance: Implications for novel antidepressant strategies.
Neuroscience Letters March 16, 2018 Jeffrey Landrigan, Farah Shawaf, Zach Dwyer et al.
The efficacy of ketamine to alleviate depressive symptoms has promoted a wealth of research exploring alternate therapeutic targets for depression. Given the caveats of ketamine treatment taken together with the increasingly greater emphasis on combinatorial therapeutic approaches to depression, we sought to asses whether the hypothalamic "hunger hormone", ghrelin, would augment the effects of...