Neurovascular plasticity of the hippocampus one week after a single dose of ketamine in genetic rat model of depression.
Hippocampus November 2016 Maryam Ardalan, Gregers Wegener, Benedetta Polsinelli et al.
Glutamatergic system and the structural plasticity hypothesis are principal components for rapid and sustained antidepressant effects of novel antidepressant therapeutics. This study represents the first investigation of the structural plasticity of the hippocampus as one of the main contributed mechanisms to the sustained anti-depressive effect of ketamine. Flinders Sensitive Line (FSL) and...
DOI: 10.1002/hipo.22617 (opens in new tab)
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Depression
Synaptic plasticity
Antidepressant
Flinders line
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