Effect of low-dose ketamine on PerioperAtive depreSsive Symptoms in patients undergoing Intracranial tumOr resectioN (PASSION): study protocol for a randomized controlled trial.
Trials August 29, 2018 Yang Zhou, Yuming Peng, Jinghan Fang et al.
Perioperative depressive symptoms (PDS) are common mental comorbidities that influence clinical outcomes and prognosis. However, there is no rapid-acting treatment to address these symptoms during a limited hospital stay. This is a single-center, randomized, placebo-controlled, and double-blind trial. Randomization will be applied and stratified by the severity of PDS (moderate versus severe)....
DOI: 10.1186/s13063-018-2831-0 (opens in new tab)
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Ketamine
Depression symptom
Perioperative
Randomized controlled trial