Björn H Schott

2 papers in the library · publishing 2018-2019

Papers

Sort Most recent Most cited

Neuronal glutamatergic changes and peripheral markers of cytoskeleton dynamics change synchronically 24 h after sub-anaesthetic dose of ketamine in healthy subjects.

Behavioural Brain Research February 1, 2019 Lejla Colic, Conor McDonnell, Meng Li et al.

Ketamine acts as a rapid-acting antidepressant by restoring glutamatergic deficits and activating synaptic plasticity processes, with peak activity 24 h after infusion. Microtubule dynamics are known to play a key role in modulation of cytoskeleton and synaptic plasticity, as well as in signalling events in peripheral blood cells. Here, we correlated ketamine-induced change in...

DOI: 10.1016/j.bbr.2018.10.021 Full text Ketamine Acet-tub Blood markers Gender specificity +1

Ketamine influences the locus coeruleus norepinephrine network, with a dependency on norepinephrine transporter genotype - a placebo controlled fMRI study.

NeuroImage: Clinical 2018 Thomas Liebe, Meng Li, Lejla Colic et al.

Ketamine is receiving increasing attention as a rapid-onset antidepressant in patients suffering from major depressive disorder (MDD) with treatment resistance or severe suicidal ideation. Ketamine modulates several neurotransmitter systems, including norepinephrine via the norepinephrine transporter (NET), both peripherally and centrally. The locus coeruleus (LC), which has high NET...

DOI: 10.1016/j.nicl.2018.09.001 Full text Ketamine Attention networks Locus coeruleus lc Norepinephrine transporter net +1