The new psychoactive substances 5-(2-aminopropyl)indole (5-IT) and 6-(2-aminopropyl)indole (6-IT) interact with monoamine transporters in brain tissue.
Neuropharmacology February 2016 Julie A. Marusich, Kateland R Antonazzo, Bruce E. Blough et al.
In recent years, use of psychoactive synthetic stimulants has grown rapidly. 5-(2-Aminopropyl)indole (5-IT) is a synthetic drug associated with a number of fatalities, that appears to be one of the newest 3,4-methylenedioxymethamphetamine (MDMA) replacements. Here, the monoamine-releasing properties of 5-IT, its structural isomer 6-(2-aminopropyl)indole (6-IT), and MDMA were compared using in...
DOI: 10.1016/j.neuropharm.2015.09.004 (opens in new tab)
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3,4-Methylenedioxymethamphetamine MDMA
5-2-aminopropylindole 5-it
6-2-aminopropylindole 6-it
Locomotor activity
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