Serotonin antagonists fail to alter MDMA self-administration in rats.
Pharmacology, Biochemistry, and Behavior September 2016 Susan Schenk, Jason Foote, Dane Aronsen et al.
Acute exposure to ±3,4-methylenedioxymethamphetamine (MDMA) preferentially increases release of serotonin (5-HT), and a role of 5-HT in many of the behavioral effects of acute exposure to MDMA has been demonstrated. A role of 5-HT in MDMA self-administration in rats has not, however, been adequately determined. Therefore, the present study measured the effect of pharmacological manipulation of...
DOI: 10.1016/j.pbb.2016.06.002 (opens in new tab)
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MDMA
Hyperactivity
Reinstatement
Self-administration
+1