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Karen M. Ryan

1 paper in the library · 4 citations · publishing 2016

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Ketamine for depression relapse prevention following electroconvulsive therapy: protocol for a randomised pilot trial (the KEEP-WELL trial)

Pilot and Feasibility Studies August 3, 2016 Martha Finnegan, Karen M. Ryan, Enda Shanahan et al. 4 citations

BACKGROUND: Major depressive disorder is a common debilitating illness that is the second leading contributor to the global burden of disease. Unfortunately, about 30 % of patients do not respond to adequate trials of antidepressants and/or psychotherapies. About 45-60 % of such treatment-resistant patients will remit with electroconvulsive therapy (ECT). However, relapse rates are high...