Therapeutic doses of ketamine acutely attenuate the aversive effect of losses during decision-making.
Elife May 3, 2024 Mariann Oemisch, Hyojung Seo
The discovery of rapid-acting antidepressant, ketamine has opened a pathway to a new generation of treatments for depression, and inspired neuroscientific investigation based on a new perspective that non-adaptive changes in the intrinsic excitatory and inhibitory circuitry might underlie the pathophysiology of depression. Nevertheless, it still remains largely unknown how the hypothesized...