Current preclinical studies on neuroinflammation and changes in blood-brain barrier integrity by MDMA and methamphetamine.
Neuropharmacology December 2014 Esther O'Shea, Andrés Urrutia, Alfred Richard Green et al.
The blood-brain barrier (BBB) is essential in the maintenance of brain homeostasis both by preserving normal brain functioning and also by protecting the brain from exposure to a range of potentially harmful substances. This review presents some of the evidence of BBB disruption following exposure to the substituted amphetamines 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and...
DOI: 10.1016/j.neuropharm.2014.02.015 (opens in new tab)
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3,4-methylenedioxymethamphetamine
Basal lamina proteins
Blood–brain barrier disruption
Igg extravasation
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