T B Nogueira

Modeling chronic brain exposure to amphetamines using primary rat neuronal cortical cultures.

Neuroscience September 26, 2014 T B Nogueira, Silvana Da Costa Araújo, F Carvalho et al.

Amphetamine-type psychostimulants (ATS) are used worldwide by millions of patients for several psychiatric disorders. Amphetamine (AMPH) and "ecstasy" (3,4-methylenedioxymethamphetamine or MDMA) are common drugs of abuse. The impact of chronic ATS exposure to neurons and brain aging is still undisclosed. Current neuronal culture paradigms are designed to access acute ATS toxicity. We report for...