MDMA ('Ecstasy'), oxytocin and vasopressin modulate social preference in rats: A role for handling and oxytocin receptors.
Pharmacology, Biochemistry, and Behavior 2016 Linnet Ramos, Callum Hicks, Alex Caminer et al.
In laboratory rats, peripheral administration of the neuropeptides oxytocin (OT) and vasopressin (AVP) induces similar prosocial effects (i.e. increased adjacent lying) to the party drug 3,4-methylenedioxymethamphetamine (MDMA), which are sensitive to vasopressin V1A receptor (V1AR) antagonism. Here, we employed a social preference paradigm to further compare the prosocial effects of OT, AVP...
DOI: 10.1016/j.pbb.2016.10.002 (opens in new tab)
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MDMA
Compound 25
Handling
Oxytocin
+3