Feasibility and tolerability of virtual reality during esketamine treatment: A pilot study.
Journal of Affective Disorders September 23, 2026 Erin Curran, Kristina T. Kumpf, Mina Ansari et al.
Ketamine/esketamine produce rapid antidepressant effects, with growing interest in how acute subjective experiences and the surrounding set and setting shape clinical outcomes. Little is known about how audiovisual adjustments during ketamine/esketamine treatment influence comfort, tolerability, or patient experience, despite their common use in clinical practice. Virtual reality (VR) is one...
DOI: 10.1016/j.jad.2026.122554 (opens in new tab)
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Esketamine
Set and setting
Treatment resistant depression
Virtual reality