Evaluating Potential Anxiolytic Effects of Minor Cannabinoids and Terpenes After Acute and Chronic Oral Administration in Rats.
Cannabis and Cannabinoid Research September 2023 Bryan W. Jenkins, Catherine F Moore, Dan P Covey et al.
Background: Cannabis and its primary psychoactive constituent delta-9-tetrahydrocannabinol (D9-THC) produce biphasic, dose-dependent effects on anxiety. In addition to D9-THC, cannabis contains other "minor" cannabinoids and terpenes with purported therapeutic potential for the treatment of anxiety. Empirical data on potential therapeutic effects of these compounds is limited. The current study...
DOI: 10.1089/can.2023.0083 (opens in new tab)
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Anxiety
Monoterpenes
Phytocannabinoids
Terpenoid