The effects of donepezil on phencyclidine-induced cognitive deficits in a mouse model of schizophrenia.
Pharmacology, Biochemistry, and Behavior December 2018 Yi-Xuan Li, Zi-He Ye, Tong Chen et al.
Donepezil is the first-line of treatment for Alzheimer's disease (AD), which improves cognitive impairment effectively, but whether it has an impact on cognitive impairment in schizophrenia remains unknown. In this study, we evaluated the effects and mechanisms of donepezil on schizophrenia-like cognitive deficits induced by phencyclidine (PCP). The cognitive deficits model of schizophrenia was...
DOI: 10.1016/j.pbb.2018.09.006 (opens in new tab)
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Cognitive deficits
Donepezil
Phencyclidine
Risperidone
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