Luke Lake

Nitrous oxide-induced subacute combined degeneration of the cord: diagnosis and treatment

Practical Neurology February 22, 2023 Álvaro París, Luke Lake, Albert Joseph et al.

Recreational use of nitrous oxide (N2O) has increased rapidly in recent years and is now the second most commonly used recreational drug among young people in the UK. There has been a corresponding rise in cases of nitrous oxide-induced subacute combined degeneration of the cord (N2O-SACD), a pattern of myeloneuropathy usually associated with severe vitamin B12 deficiency. This can cause...