Ian Yates

Sex and individual differences in ketamine's effects on alcohol drinking in rats.

Alcohol Clin Exp Res March 1, 2026 Sarah D Jennings, Ian Yates, Samantha K Saland et al.

Background: Effective pharmacotherapies for Alcohol Use Disorder (AUD) are lacking, and factors such as sex, drinking patterns, and timing of treatment during the addiction cycle may influence treatment efficacy. Clinical studies suggest that ketamine may be effective in AUD; however, preclinical findings have been inconclusive, likely due to varying rodent strains, intake protocols, and...