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James W Y Chen

2 papers in the library · 68 citations · publishing 2020-2021

Papers

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A qualitative and quantitative account of patient's experiences of ketamine and its antidepressant properties.

Journal of Psychopharmacology August 1, 2021 Rachael Sumner, Emme Chacko, Rebecca McMillan et al. 68 citations

Ketamine is central to one of the most rapidly growing areas of neuroscientific research into novel treatments for depression. Limited research has indicated that the psychedelic properties of ketamine may play a role in its antidepressant effects. The aim of the current study was to explore the psychedelic experiences and sustained impact of ketamine in major depressive disorder. In the...

Acute Effects and the Dreamy State Evoked by Deep Brain Electrical Stimulation of the Amygdala: Associations of the Amygdala in Human Dreaming, Consciousness, Emotions, and Creativity.

Frontiers in Human Neuroscience February 25, 2020 George Lai, Jean-Philippe Langevin, Ralph J. Koek et al.

Accurate localization of complex human experiences such as emotions, dreaming, creativity, and consciousness to specific cerebral structures or neural networks has remained elusive despite technological advances. We report the use of acute deep brain stimulation (DBS) to evoke behavioral and emotional effects by applying electrical stimulation (ES) at various voltage strengths to the...