Altered static and dynamic functional network connectivity between subcortical nuclei and cortical regions of the default mode network in type 2 diabetes mellitus.
Frontiers in Neuroscience January 28, 2026 Dongsheng Zhang, Xiaoling Zhang, Lei Wang et al.
Introduction: Disruptions in functional connectivity (FC) within the default mode network (DMN) are well established as a key neuropathology underlying cognitive impairment in type 2 diabetes mellitus (T2DM). Subcortical nuclei, including the basal forebrain (BF) and mediodorsal thalamus, play critical roles in regulating DMN-associated cognitive processes and are particularly vulnerable to...
DOI: 10.3389/fnins.2026.1766192 (opens in new tab)
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Default mode network
Dynamic
FMRI
Subcortical
+2