A cost-utility analysis of mindfulness-based cognitive therapy versus cognitive behavioral therapy for major depressive disorder relapse prevention in primary care.
Psychiatry Research February 4, 2026 Waseem Abu-Ashour, Rick Audas, John-Michael Gamble et al.
Background: Major depressive disorder (MDD) is a chronic condition with high relapse rates affecting patients and health systems. Cognitive behavioral therapy (CBT) and mindfulness-based cognitive therapy (MBCT) are strategies for relapse prevention, but their comparative long-term cost-effectiveness remains unclear. Methods: We developed a cohort-based Markov model with three health states,...