Gisela Mezquida

2 papers in the library · 5 citations · publishing 2019-2023

Papers

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Exploration of cannabis use and polygenic risk scores on the psychotic symptom progression of a FEP cohort

Psychiatry Research May 8, 2023 Alex Gonzalez Segura, Anna Mané, L. Prohens et al. 5 citations

Cannabis use is highly prevalent in first-episode psychosis (FEP) and plays a critical role in its onset and prognosis, but the genetic underpinnings promoting both conditions are poorly understood. Current treatment strategies for cannabis cessation in FEP are clearly inefficacious. Here, we aimed to characterize the association between cannabis-related polygenic risk scores (PRS) on cannabis...

DOI: 10.1016/j.psychres.2023.115249

Gene-environment interaction between an endocannabinoid system genetic polymorphism and cannabis use in first episode of psychosis.

European Neuropsychopharmacology June 1, 2019 Miquel Bioque, Sergi Mas, M. Costanzo et al.

Alterations of the endocannabinoid system (ECS) may play an important role in the development of schizophrenia and other psychotic disorders. Cannabis use is one of the environmental factors more repeatedly related to an increase the risk of developing a psychotic episode, while its use modifies the ECS normal function. In the present study we purposed to examine the gene by environment (GxE)...

DOI: 10.1016/j.euroneuro.2019.04.005