Blood-based biomarkers of antidepressant response to ketamine and esketamine: A systematic review and meta-analysis
Molecular Psychiatry June 27, 2022 Gustavo C. Medeiros, T. Gould, W. Prueitt et al.
(R,S)-ketamine (ketamine) and its enantiomer (S)-ketamine (esketamine) can produce rapid and substantial antidepressant effects. However, individual response to ketamine/esketamine is variable, and there are no well-accepted methods to differentiate persons who are more likely to benefit. Numerous potential peripheral biomarkers have been reported, but their current utility is unclear. We...