Ketamine, Esketamine, and A New Generation of Antidepressants
Psychiatric Annals February 1, 2020 Samuel T. Wilkinson, Brandon M. Kitay
Since the discovery of its rapid-acting antidepressant properties, ketamine has helped stimulate a new line of research in the development of rapid-acting antidepressants based on the glutamate and gamma-aminobutyric acid neurotransmitter systems. An intranasal version of the S-enantiomer of ketamine (esketamine) recently received regulatory approval as a therapy for treatment-resistant...