Sex-Dependent Attentional Impairments in a Subchronic Ketamine Mouse Model for Schizophrenia
Biological Psychiatry Global Open Science May 29, 2023 Daisy L. Spark, Sherie Ma, Cameron J. Nowell et al. 5 citations
Background: The development of more effective treatments for schizophrenia targeting cognitive and negative symptoms has been limited, partly due to a disconnect between rodent models and human illness. Ketamine administration is widely used to model symptoms of schizophrenia in both humans and rodents. In mice, subchronic ketamine treatment reproduces key dopamine and glutamate dysfunction;...