Effect of postoperative application of esketamine on postoperative depression and postoperative analgesia in patients undergoing pancreatoduodenectomy: a randomized controlled trial protocol.
Trials August 19, 2023 Kaili Yu, Zhenguo Song, Bowen Zhang et al.
Pancreatoduodenectomy (PD) is traumatic, difficult to perform, and has a high incidence of postoperative complications and perioperative mortality. Postoperative complications and pain occur frequently and seriously affect the psychological status of patients. Esketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, has analgesic and antidepressant effects. In this study, we aim to...
DOI: 10.1186/s13063-023-07575-8 (opens in new tab)
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Esketamine
Pancreatoduodenectomy
Postoperative analgesia
Postoperative depression