The effect of ketamine on affective modulation of the startle reflex and its resting-state brain correlates
Scientific Reports August 16, 2023 Zümrüt Duygu Sen, Tara Chand, Lena Vera Danyeli et al.
Ketamine is a rapid-acting antidepressant that also influences neural reactivity to affective stimuli. However, the effect of ketamine on behavioral affective reactivity is yet to be elucidated. The affect-modulated startle reflex paradigm (AMSR) allows examining the valence-specific aspects of behavioral affective reactivity. We hypothesized that ketamine alters the modulation of the startle...