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Miriam Vignando

2 papers in the library · 7 citations · publishing 2024-2026

Papers

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Deviations in effective connectivity explain different hallucination subtypes in Parkinson’s disease psychosis

Nature Mental Health June 1, 2026 Miriam Vignando, Dominic H Ffytche, N. Mazibuko et al.

Psychosis and visual hallucinations (VH) in Parkinson’s disease (PD) substantially impact patient outcomes, yet the underlying neural mechanisms remain unclear, limiting effective treatments. Here we used dynamic causal modeling to leverage the fast temporal dynamics captured with electroencephalography data during a visual mismatch negativity task in people with PD with (N = 20) and without (N...

Visual mismatch negativity in Parkinson's psychosis and potential for testing treatment mechanisms

Brain Communications 2024 Miriam Vignando, Dominic H Ffytche, Ndaba Mazibuko et al. 7 citations

Abstract Psychosis and visual hallucinations are a prevalent non-motor symptom of Parkinson's disease, negatively affecting patients’ quality of life and constituting a greater risk for dementia. Understanding neural mechanisms associated to these symptoms is instrumental for treatment development. The mismatch negativity is an event-related potential evoked by a violation in a sequence of...