Deafferentation and Network Dysregulation Hypotheses in Charles Bonnet Syndrome (CBS) Mechanisms
January 17, 2026 Colin Chien
Charles Bonnet Syndrome (CBS) is a rare condition characterized by complex, persistent visual hallucinations (VH) in patients with normal cognitive function and vision impairment.At present, the cause of CBS remains unclear; there is evidence that deafferentation, hallucinations caused by a deprivation of visual stimuli, which propagates neural hyperactivity through cortical excitability, is...