Electroconvulsive therapy disrupts functional connectivity between hippocampus and posterior default mode network.
Progress in Neuro-psychopharmacology and Biological Psychiatry February 1, 2024 K. Gbyl, Vytautas Labanaukas, C. C. Lundsgaard et al.
BACKGROUND The mechanisms underlying memory deficits after electroconvulsive therapy (ECT) remain unclear but altered functional interactions between hippocampus and neocortex may play a role. OBJECTIVES To test whether ECT reduces functional connectivity between hippocampus and posterior regions of the default mode network (DMN) and to examine whether altered hippocampal-neocortical functional...