PLoS BiologyMarch 10, 2026Ali Rezaei, Corson N. Areshenkoff, Daniel J. Gale et al.
Motor learning induces alterations in neural activity that can persist long after the effects of such learning have faded. These persistent neural alterations are thought to manifest behaviorally as "savings," or faster relearning, via access to a latent motor memory. How the human brain forms and retrieves these latent memories, and the specific neural systems involved, remains unresolved....
PLoS BiologyAugust 1, 2025A. Rezaei, Corson N. Areshenkoff, Daniel J. Gale et al.
An often-desired feature of motor learning is that it generalizes to untrained scenarios. Yet, how this is supported by brain activity remains poorly understood. Here we show, using human functional MRI and a sensorimotor adaptation task involving the transfer of learning from the trained to untrained hand, that the transfer phase of adaptation re-instantiates a highly similar large-scale...