Carles Colom-Rocha

2 papers in the library · 3 citations · publishing 2024-2026

Papers

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Evaluating whether a therapeutic dose of ketamine exposure during adolescence influences adult vulnerability in rats to commonly abused drugs.

Psychopharmacology October 26, 2026 Jordi Jornet-Plaza, Carles Colom-Rocha, M Julia García-Fuster

Rationale Ketamine has emerged as a rapid-acting antidepressant drug for treatment-resistant depression in adults and is currently evaluated for adolescent depression. However, the long-term effects of ketamine exposure during this period of brain development remain unclear, particularly regarding addiction liability. Objectives To investigate whether repeated ketamine exposure during...

DOI: 10.1007/s00213-026-07195-5 Full text Ketamine Treatment-resistant depression Adolescence Rapid antidepressant +2

Cannabidiol or ketamine for preventing the impact of adolescent early drug initiation on voluntary ethanol consumption in adulthood.

Frontiers in Pharmacology 2024 Carles Colom-Rocha, Cristian Bis-Humbert, M Julia García-Fuster 3 citations

Few studies have previously evaluated the long-term impact of initiating the combined use of alcohol and cocaine early-in-life during adolescence. Our preclinical study characterized changes in affective-like behavior and/or voluntary ethanol consumption emerging later on in adulthood induced by a prior adolescent drug exposure, as well as tested therapeutical interventions (i.e., cannabidiol...

DOI: 10.3389/fphar.2024.1448170 Full text Alcohol use disorder Addiction risk factors Adolescence Rodent models +7