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M. Moretti

1 paper in the library · publishing 2025

Papers

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The epigenetic mechanisms of ketamine in the treatment of depression: a systematic review.

Epigenomics November 7, 2025 Ivana Leccisotti, M. Moretti, Mario Altamura et al.

AIM Ketamine antidepressant effects go beyond immediate receptor action, involving lasting transcriptional and epigenomic changes that support its rapid, long-lasting benefits. The present systematic review synthesized existing preclinical and clinical evidence on the epigenetic mechanisms of ketamine in the treatment of depression. METHODS A comprehensive search of three electronic databases...

DOI: 10.1080/17501911.2025.2583892