Esketamine for Treatment-Resistant Depression: A Case Series and Literature Review.
Cureus September 2025 Muhammad Abbas, David B Adams, Jack Noto et al.
Management of treatment-resistant depression (TRD) is complex and frustrating for patients, requiring several treatment courses before (or without) achieving remission. This investigation aims to highlight and analyze real-world instances of using esketamine for patients with TRD who have failed electroconvulsive therapy (ECT). Four case reports from a single Hackensack-Meridian care center are...
DOI: 10.7759/cureus.92165 (opens in new tab)
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Esketamine
Treatment-resistant depression
Case report series
Literature review