Ketamine modulates the exploratory dynamics and homebase-related behaviors of adult zebrafish.
Pharmacology, Biochemistry, and Behavior December 1, 2024 Camilla W Pretzel, João V Borba, Cássio M Resmim et al. 5 citations
Anxiety can be a protective emotion when animals face aversive conditions, but is commonly associated with various neuropsychiatric disorders when pathologically exacerbated. Drug repurposing has emerged as a valuable strategy based on utilizing the existing pharmaceuticals for new therapeutic purposes. Ketamine, traditionally used as an anesthetic, acts as a non-competitive antagonist of the...
DOI: 10.1016/j.pbb.2024.173892 (opens in new tab)
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Nmda receptor
Open field test
Spatio-temporal exploration
Stereotyped behavior
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